Beckman Coulter Multisizer 4 Particle Counter

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The Beckman Coulter Multisizer 4 particle counter is a reliable accurate realtime, multichannel analyzer with high reproducibility. Being 21 CFR part 11 compliant makes this particle counter a valuable asset for both research and development, as well as quality control in either an industrial or life science environment. The Beckman Coulter Multisizer 4 particle counter uses a unique digital pulse processing method in combination with the Electrical Sensing Zone, that provides dynamic size measurements and counting in real time with an overall size range of 0.4 µm to 1600 µm. Using a mercury free “Isolated pistion” the Beckman Coulter Multisizer 4 draws the suspension through the aperture either metered, or continuous flow, depending on needs, with options to allow users defined parameters based on particle count or elapsed time. Measurements are also multifactorial, providing information like number, volume, surface area size distributions and mass all in one measurement. Increased resolution and high speed digitalization gives you a more accurate characterization, with the use of various pulse parameters.

The Beckman Coulter Multisizer 4 particle counter is user friendly, controlled with an external PC using windows based software with wizards to help guide beginning users and drop down dialogue boxes giving access to all settings for more experienced users.  Statistical parameters as well as size and pulse data are automatically calculated by the Multisizer software, presenting a customized report of the results in numerous formats. Data may be stored for supplementary analysis or reporting at a later time, eliminating the need to run the sample again.  The EZAccess reagent management system helps to administrate reagents and waste. 

Beckman Multisizer 4 Specifications:

Particle Size Analysis Range:    

0.4 µm to 1600 µm in diameter.  0.033 fL to 2.145 x 109 fL or µm3 in volume.

Number of Channels: 

Pulse data is digitized and can be processed to achieve up to 400 size channels for a selected pulse range. Number of channels and range can be reprocessed as necessary.

Aperture Tube Analysis Range:    

Total range: 2% to 80% of aperture diameter.

Standard Range:             

2% to 60% of aperture diameter

Dynamic Range of Aperture:

Standard 1:30 (by diameter) Total 1:40 (by diameter) Standard 1:27,000 (by volume) Total 1:64,000 (by volume)


± 1% for diameter ± 3% for volume

Metering System:

Mercury-free, wide range metering pump

Power Requirements: 

Less than 55 volt-amps (watts)

Regulatory Compliance: 

The software enables 21 CFR Part 11 compliance


User selectable

Volumetric Pump Accuracy: 

Better than 99.5%

Operating Altitude: 

Up to 2000 m (6560 ft)

Operating Temperature: 

5°C to 40°C

Aperture Current Accuracy:

± 0.4% of setting

Aperture Current Range: 

30 µA - 6000 µA in 0.2 µA steps

Aperture Diameter: 

(nominal diameters)

20 µm to 2000 µm apertures

Digital Pulse Processor:

Proprietary high-speed digitalization of the signal.

Electrolyte Solutions:        

All aqueous and non-aqueous electrolyte solutions recommended for use with aperture technology will be suitable for use with the Multisizer 4. Electrolytes should be compatible with glass, fluoropolymers, fluoroelastomers and stainless steel.

Environmental Conditions:

a) This instrument is safe for indoor use only.
 b) Installation category: 11.
 c) Pollution degree: 1.

Fuse Types: 

250 V, IEC (5x20 mm), Time delay (TD), 2.0 A

Modal Count Mode:

10 to 100,000 counts

Polarity Error:

Less than 0.5%

Pulse Data:

Time stamped pulses up to 525,000 per single analysis.

Pulse Distribution Data: 

Pulse distribution by time, sequence and width for pulse height diameter, pulse  height volume, pulse height volt, pulse width, pulse area, average pulse height  diameter, average pulse height volume and average pulse width. 

Number Size Distribution Data:

Size distribution by diameter, volume and area for number, number%, number/ml, volume, volume%, volume/ml, surface area, surface area% and surface area/ml.

Supply Frequency:

47 to 63 Hz inclusive

Time Mode: 

0.1 to 999 seconds, selectable in 10 ms increments. Typically, time analysis is 10 to 90 seconds.

Total Count Mode:  

50 to 500,000 counts

Volumetric Mode:  

Continuously selectable from 50 µL to 2000 µL


100 lbs


25x24x20 "


100 - 120 VAC; 230 - 240 VAC ± 10%; single phase

  • Beckman Coulter Multisizer 4 Particle Counter 
  • Windows 7 Notebook with MS4 Software
  • Validation Report
  • 70µm Aperture
  • Brand New Stirrer Paddle with Motor
  • All Required Cables
  • Operator's Guide
  • 30-Day Warranty

The Beckman Coulter Multisizer 4 Particle Counter has been inspected, tested and is in excellent condition. The platform and position sensor have been replaced with brand new components. If you have any questions about this analyzer, please don't hesitate to contact us. 

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