Biotage Isolera One Flash Chromatography System

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The Biotage Isolera One Accelerated Chromatographic Isolation system provides easy to operate flash chromatography in a compact and robust system.  This single channel, single collection bed flash system has a variable detector with a bandwidth range of 200-400 nm and a fraction capacity of up to 9.6 liters.  The flow rate of this flash chromatograph can be set between 1 and 200 mL per minute and features a gradient optimization that reduces solvent use by up to 60%.

The Isolera One Flash Chromatography system features a full color touch screen control that guides users through a window based interface allowing them to select and edit methods quickly and easily. From this interface users can change gradient points of this chromatograph, edit segments, flow rate, collection volume, fraction wavelengths and modes or add extra collection racks all while a run is in progress. Methods for the Isolera system can be transferred to other Isolera Systems for increased throughput. These Accelerated Chromatographic Isolation systems are also optimized for Biotage SNAP, SNAP Ultra, ZIP and ZIP Sphere cartridges from 5g up to 750g sizes.

Biotage Isolera One Accelerated Chromatographic Isolation system Specifications:

System Control & Data Management 

On-board computer with 10.4” touch screen interface

Wave length 

200–400 nm 

UV Detector 


Collector Bed 


Flow Cell Path Length 

0.3 mm  

Fractionation Modes 

Volume, threshold, threshold with volume, low slope, medium slope, custom slope or via external detection

Collection Vessels 

Test tubes (13 mm, 16 mm, 18 mm, and 25 mm) and bottles (120 mL, 240 mL, and 480 mL)

Solvent Delivery 

Two constant volume (3 mL) electric HPFC pumps

Flow Rate 

1–200 mL/min 

Pressure Limit  

145 psi (10 bar)

Sample Interval 

Milligrams–75 grams 


100–240 VAC, 50/60 Hz, 4.0 A 





  • Biotage Isolera One Flash Chromatography system IOS-1SV
  • Touch Screen Controller with Built-In Isolera Software 
  • 18x150mm Racks
  • Biotage Isolera System Validation Report
  • Operator's Guide
  • Power Cord
  • 30-Day Warranty

This Isolera One Flash Chromatography system has been fully inspected and comes with current validation reports. All of our lab equipment comes backed with our standard warranty. Should you have any questions, please don't hesitate to contact us.

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