Biotage Isolera One Flash Chromatograph

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The Biotage Isolera One Flash Chromatography System brings you an advanced, fully automated compound purification in one compact package. This flash chromatograph features variable/two UV wavelength detectors with real time PDA scanning. The Isolera One has a flow rate of between 1 and 200 mL per minute, and a fraction capacity of up to 9.6 Liters.

The Biotage Isolera One Flash Chromatography System is controlled through a windows based, user-friendly touch screen that’s fast and accurate in its response time. Users can select their protocols, including TLC to Step Gradient, as well as transfer methods to other Isolera systems. Using both wavelengths in this flash chromatograph ensures the collection of UV absorbing compounds to avoid wasting products and solvents filling tubes. These flash chromatography systems are also optimized for Biotage SNAP, SNAP Ultra, ZIP and ZIP Sphere cartridges from 5g up to 750g sizes. All of our Biotage Isolera systems come fully tested and validated by our service team.

Biotage Isolera One Flash Chromatograph Specifications:

Wave length 

200–400 nm 

UV Detector 


Collector Bed 


Solvent Delivery 

Two constant volume (3 mL) electric HPFC pumps

Flow Rate 

1–200 mL/min 

Pressure Limit  

145 psi (10 bar)

Sample Interval 

Milligrams–75 grams 

UV Detection  

Choice of variable wavelength (200–400 nm), fixed (254 nm), or UV-VIS (200–800 nm) detectors

Flow Cell Path Length 

0.3 mm  

UV Collection Modes   

Single/dual/λ-All wavelengths (variable UV and UV-VIS)

Fractionation Modes 

Volume, threshold, threshold with volume, low slope, medium slope, custom slope or via external detection

Collection Vessels 

Test tubes (13 mm, 16 mm, 18 mm, and 25 mm) and bottles (120 mL, 240 mL, and 480 mL)


100–240 VAC, 50/60 Hz, 4.0 A 

System Control & Data Management 

On-board computer with 10.4” touch screen interface





  • Biotage Isolera One Flash Chromatograph
  • 25ML Racks (4qty)
  • Touch Screen Controller
  • Validation Report with Clean Bill of Health
  • 115V Power Cord
  • Operator's Manual
  • 30-Day Warranty

These Biotage Isolera One Flash Chromatograph have been thoroughly inspected and are performing to factory specifications. All of our lab equipment comes backed with our standard warranty. Should you have any questions, please don't hesitate to contact us.

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