AB Sciex 4500 Triple Quad LCMS System

Mass Spectrometers
AB Sciex
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The AB Sciex 4500 Triple Quad LCMS has built upon the popular Sciex 4000 QQQ Mass Spectrometer platform and made it even better.  The Sciex 4500 has been redesigned with intelligence and performance in mind. This triple quadrupole mass spectrometer brings you the best in quantitative sensitivity and robustness to expand upon the experiments going beyond MRM, and gives you substantial improvements in data quality. The Sciex uses it’s quantitative and qualitative sensitivity to detect low analyte concentrations, a dynamic range for high to low concentrations, scan speed, and ionization source flow range. This potent lcms is equipped with Linear Ion Trap technology for more reliable quantitation over long runs.

The AB Sciex 4500 Triple Quad  LC/MS is an ideal choice for research based labs dealing with regulated bioanalysis, targeted quantitative proteomics, clinical research, screening for contaminants in food or the environment, as well as ADME. The Sciex 4500 is also ideal for drug screen and pain management laboratories.  This liquid chromatography mass spectrometer has been designed from the inside out to offer a powerful tool that’s more compact to take up less valuable lab space. The triple quad 4500 is also an ideal choice for UHPLC, with fast precise quantitation and ultra-fast scan speeds. This quadrupole mass spectrometer has short dwell times, as low as 1 ms, and can scan for more compounds in a single experiment than ever before, using the powerful MRM program to automatically optimize your acquisitions. 

The AB Sciex Triple Quad 4500 LC/MS use triple quads equipped with linear accelerator trap technology, that delivers up to a 100-fold increase to MS/MS sensitivity, and gives a more accurate detection, quantification and confirmation of compounds. The powerful Sciex lcms lets you acquire a complete MS/MS spectrum for every compound detected and cross references it with a built-in library for confirmation. With the computational power behind this LCMS, you’re able to develop new methods, and better streamline your existing work flow. The AB Sciex Triple Quad 4500 LC/MS also features QJet Ion Guide for better ion containment, AcQurate Pulse counting detector for improved extraction efficiency. Contact us today to learn more about our AB Sciex 4500 Triple Quadrupole LC/MS system.

AB Sciex 4500 Triple Quad Mass Spectrometer Specifications:

Sensitivity MRM  mode Reserpine 200 fg on column S/N > 2000  C.V. < 5%
Maximum scan speed 12,000 Da/sec
Polarity switching time 50 msec, in MRM and scheduled MRM (sMRM) modes
Minimum MRM dwell time 1 msec
Mass range (m/z) 5-2000 
Cross talk for reserpine 609/195 

<0.5% cross talk detectable with 2 msec dwell time and 3 msec inter-MRM pause time

Triple quadrupole mass stability 0.1 Da over 24 hours
Scan types 

Full scan MS and selected ion MS for both Q1 and Q3, product ion scan, precursor ion scan, neutral loss or gain scan, multiple reaction monitoring (MRM), and scheduled MRM (sMRM)

Detector type AcQuRate Pulse Counting CEM
Dynamic range 4 orders of magnitude
Ionization sources Turbo V source housing with TurboIonSpray probe or APCI probe.
Maximum temperature 750ºC
Flow rate compatibility   5 μL/minute to 3 mL/minute
Power208V 50/60Hz AB Sciex 4500, 208V Vacuum Pump, 208V Peak N2 Generator, 115V Shimadzu UPLC
Dimensions37" x 33" x 55" Sciex 4500

  • AB Sciex 4500 Triple Quad LCMS System
  • Multi Spray S/N 27318130306
  • Windows 7 Desktop Dell Optiplex 9010 with Analyst 1.6.2 Software (installed)
  • LCD Monitor
  • MultiQuant 2.1 Software (installed)
  • PAL Loader Software (installed)
  • Team Viewer 10 Post Software (installed)
  • CD with Instrument Optimization Files
  • Tune Report from 08/2017
  • Peak Genius 122 Nitrogen Generator
  • Nitrogen Regulator
  • Big Universal Trap Nitrogen Purifier Model N RMSN-4
  • Peak Generator Isolation Cart
  • Shimadzu Prominence UFLC
    Shimadzu DJU-20A-5R Degasser
    Shimadzu LC-20ADXR LC
    Shimadzu CTO-20AC Column Oven
    Shimadzu Reservoir Tray
  • ExSigent PAL HTS-XT Autosampler
  • Powervar Uninterupted Power Supply
  • Mass Spec Exhaust Waste Bottle
  • SOEGVAC SV28 BI Vacuum Pump Model SV28BI
  • Power Cables
  • Communication Cables
  • Operator's Manual
  • Warranty  

This listing is for a slightly used AB Sciex 4500 Triple Quad LCMS system.  The Mass Spectrometer is in excellent working condition. System has a clean bill of health and is ready to ship. System comes fully tuned and backed by our 30-day warranty within the U.S.  One year service agreements available for an additional and include the following service on:

LC/MS System:
AB Sciex 4500 Triple Quad LCMS System
Shimadzu Prominence UFLC
Shimadzu DJU-20A-5R Degasser
Shimadzu LC-20ADXR LC
Shimadzu CTO-20AC Column Oven
Shimadzu Reservoir Tray

Full Maintenance Service Agreement Features:
30 minute telephone response
48-72 hour system down on-site response target
One scheduled Planned Maintenance Inspection/unit/year All remedial parts, labor and expenses.

Please note: nitrogen generators are not included as part of service agreement and falls under our 30-day right of return warranty.  Installation required by The Lab World Group is required in order to receive a warranty, or one year service agreement.  Should you have any questions about this Sciex 4500 LCMS system, please don't hesitate to contact us. 

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